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नवीनतम संदेश 2
2022-08-28 21:49:01
Educational objective: Exposure to ionizing radiation, including therapeutic and palliative radiation therapy, induces DNA damage through DNA double-strand fractures and the formation of oxygen free radicals.
204 views18:49
2022-08-28 20:19:38
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175 views17:19
2022-08-28 08:48:01
22 voters225 views05:48
2022-08-28 08:48:01
A 23-year-old previously healthy man comes to the office after noticing a painless, hard mass in the left testis. Scrotal ultrasound shows a solid testicular mass, and CT scan of the abdomen and pelvis shows left paraaortic lymphadenopathy. Left orchidectomy is performed and postoperative histopathology reveals seminoma of the testis. External beam radiotherapy is administered to the paraaortic metastatic area . Several weeks later, the retroperitonea1 nodes are observed to have markedly decreased in size.
219 views05:48
2022-08-27 21:47:01
Educational objective: Bloom syndrome is a rare autosomal recessive condition caused by mutations in the BLM gene encoding helicase, an enzyme that unwinds the double helix during DNA replication. Patients typically present with growth retardation, facial anomalies, photosensitive skin rash, and immunodeficiency due to chromosomal instability and breakage.
247 views18:47
2022-08-27 08:47:01
28 voters280 views05:47
2022-08-27 08:47:01
245 views05:47
2022-08-26 21:46:01
Educational objective: The genetic code is considered "degenerate" because more than 1 codon can code for a particular amino acid. Some of this degeneracy is explained by the wobble hypothesis, which states that the first 2 nucleotide positions on the mRNA codon require traditional (Watson-Crick) base pairing, whereas the third "wobble" nucleotide position may undergo less stringent (nontraditional) base pairing.
262 views18:46
2022-08-26 08:45:17
28 voters309 views05:45
2022-08-26 08:45:16
A researcher develops 2 functional mRNA sequences composed of CUC and CUU trinucleotide repeats, respectively. He subsequently incubates these mRNAs in a solution containing functional ribosomes and tRNAs charged with the appropriate amino acids. After several hours, it is found that both mRNA sequences produce polypeptide chains containing leucine repeals.
290 views05:45
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