Educational objective: All 3 prokaryotic DNA polymerases can r | USMLE Biochemistry Videos & Books

Educational objective: All 3 prokaryotic DNA polymerases can remove mismatched nucleotides via their 3' to 5' exonuclease ("proofreading") activity. Only DNA polymerase I has 5' to 3' exonuclease activity, which is used to remove the RNA primer synthesized by RNA primase.