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33-year-old woman, gravida 2 para 1, comes to the office for a | USMLE Biochemistry Videos & Books

33-year-old woman, gravida 2 para 1, comes to the office for a prenatal visit at 20 weeks gestation. She feels well and reports experiencing fetal movements. The patient has no medical problems other than a history of cleft lip, which was repaired in childhood. Her husband is healthy, but her previous child was
born with spina bifida. She takes a daily prenatal vitamin. Physical examination is unremarkable and uterine size is in accordance with ultrasound dates. The patient is worried that the fetus may develop the same birth defect as her previous child.