Educational objective: Translation of the mRNA template procee | USMLE Biochemistry Videos & Books

Educational objective: Translation of the mRNA template proceeds in the 5' to 3' direction. Because complementary sequences align in antiparallel fashion, during translation tRNA anticodons will be oriented in the opposite 3' to 5' direction. Stop codons (UAA, UAG, and UGA) halt protein synthesis by binding a release factor; they do not add amino acids to the polypeptide chain.